10 Best allergy medicines of 2025

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Best Choice

1

Allegra
Allegra Adult 24-Hour Allergy Relief Tablets, Non-Drowsy Indoor and Outdoor Allergy Medicine, 180 mg Fexofenadine HCI Antihistamine Pill, 100-Count

20% Off
Main highlights

24-Hour Relief
One tablet provides round-the-clock relief from allergy symptoms.

Versatile Allergy Use
Effective for indoor, outdoor, seasonal, and pet allergies.

Convenience and Availability
Praised for being easy to carry and readily available.
Key specs
- dosage:24-hour
- form:tablet
- active ingredient:fexofenadine HCI
- usage instructions:One tablet daily
- symptom relief:sneezing, runny nose, itchy eyes
9.8

Exceptional

Our Rating
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Value for Money

2

Zyrtec
Zyrtec 24 Hour Allergy Relief Tablets, Indoor & Outdoor Allergy Medicine with 10 mg Cetirizine HCl Antihistamine for Allergies, Bundle of one, 30 ct Bottle & Three,1 ct Travel Packs
Main highlights

Powerful 24-Hour Relief
Provides all-day relief from indoor and outdoor allergy symptoms with a single dose.

Versatile Allergy Solution
Ideal for treating allergies caused by dust, mold, pet dander, pollen, weeds, and grasses.

Highly Praised Effectiveness
Customers appreciate its ability to stop itching and provide relief.
9.7

Exceptional

Our Rating
3

ValuMeds
ValuMeds 24-Hour Allergy Medicine Antihistamine for Pollen, Hay Fever, Dry, Itchy Eyes, Allergies | Cetirizine HCl 10mg Caplets, Compare to Leading Brand (300 Count (Pack of 1))
Main highlights

24-Hour Allergy Relief
Experience effective, long-lasting relief from allergies with cetirizine hydrochloride.

Ideal for Busy Lifestyles
Non-drowsy formula perfect for work, school, or daily activities.

Highly Rated Value
Customers appreciate the quality and cost-effectiveness compared to brand names.
9.5

Excellent

Our Rating

9.9
simple to consume

9.3
worth the money

9.3
quality of ingredients
4

Amazon Basic Care
Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 30 Count (Packaging may vary)
Main highlights

24-Hour Relief
Provides up to 24 hours of relief from allergy symptoms.

Indoor Outdoor Use
Ideal for both indoor and outdoor allergy symptom relief.

Prescription Strength
Praised for its original prescription strength effectiveness.
Key specs
- dosage:10 mg
- form:tablets
- active ingredient:cetirizine hydrochloride
- usage instructions:24-hour relief
- symptom relief:allergy symptoms
9.4

Excellent

Our Rating
5

HealthA2Z

HealthA2Z® Allergy Relief | Cetirizine 10mg | All Day Allergy Relief | Indoor & Outdoor | Relief from Itchy Throat, Sneezing, Runny Noses (300 Count (Pack of 1))
9.1

Excellent

Our Rating
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6

Amazon Basic Care
Amazon Basic Care Allergy Relief Diphenhydramine HCl 25 mg, Antihistamine Tablets for Symptoms Due to Hay Fever and Upper Respiratory Allergies, 100 Count
Main highlights

Powerful Antihistamine Relief
Contains 25 mg diphenhydramine HCl for effective multi-symptom allergy relief.

Nighttime Allergy and Cold Relief
Ideal for alleviating symptoms like sneezing and runny nose at night.

Affordable and Effective Sleep Aid
Praised for being a cost-effective alternative to name brands with similar efficacy.
9.0

Excellent

Our Rating

9.9
simple to consume

9.7
worth the money

9.3
Flavor
7

Xyzal
Xyzal 24 Hour Allergy Relief Medicine, Original Prescription Strength Antihistamine, Levocetirizine Dihydrochloride Tablets, 5 mg, 35 Count

28% Off
Main highlights

Key Features
Rapid relief in one hour, 24-hour allergy symptom control, full prescription strength without a prescription.

Ideal Use Cases
Effective for nighttime use, providing relief from severe pollen allergies and preventing morning discomfort.

Customer Praise
Most reviews highlight its quick effectiveness and all-day relief, significantly improving quality of life during allergy season.
8.9

Very Good

Our Rating

9.7
simple to consume

8.7
worth the money
8

GoodSense
GoodSense All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 365 Count
Main highlights

24-Hour Relief from Allergies
Provides temporary relief from hay fever and upper respiratory allergies for 24 hours.

Ideal for Both Indoor and Outdoor Use
Effective against common allergy symptoms whether you're inside or outside.

Affordable Alternative to Brand Names
Praised for being cost-effective compared to brand-name options like Zyrtec.
8.6

Very Good

Our Rating

9.9
simple to consume

9.9
worth the money
9

Amazon Basic Care
Amazon Basic Care Allergy Relief Loratadine Tablets 10 mg, 90 Count (Packaging may vary)
Main highlights

Key Features
Loratadine 10 mg offers 24-hour non-drowsy allergy relief, comparable to Claritin, without causing sleepiness.

Ideal Use Cases
Best for relieving hay fever, sneezing, runny nose, itchy throat, and watery eyes due to upper respiratory allergies.

Customer Praise
Most reviews highlight its effectiveness in allergy relief without the drowsiness as the most appreciated benefit.
8.5

Good

Our Rating

9.9
simple to consume

9.3
worth the money

9.1
Flavor
10

GoodSense
GoodSense Allergy Relief Loratadine Tablets 10 mg, Antihistamine, Allergy Medicine for 24 Hour Allergy Relief, 365 Count
Main highlights

24 Hour Non-Drowsy Relief
GoodSense Loratadine provides 24-hour allergy relief without drowsiness, ideal for daily use.

Ideal for Outdoor Allergies
Effective against hay fever and pollen allergies, perfect for outdoor enthusiasts.

Cost-Effective Year Supply
Praised for its affordability and effectiveness compared to brand names like Claritin.
8.4

Good

Our Rating

9.9
simple to consume

9.3
worth the money

9.1
Flavor

10 Best allergy medicines of 2025

1

Allegra Adult 24-Hour Allergy Relief Tablets, Non-Drowsy Indoor and Outdoor Allergy Medicine, 180 mg Fexofenadine HCI Antihistamine Pill, 100-Count

How do we rank?

How do we rank?

Analyzing top stores

2

Zyrtec 24 Hour Allergy Relief Tablets, Indoor & Outdoor Allergy Medicine with 10 mg Cetirizine HCl Antihistamine for Allergies, Bundle of one, 30 ct Bottle & Three,1 ct Travel Packs

3

ValuMeds 24-Hour Allergy Medicine Antihistamine for Pollen, Hay Fever, Dry, Itchy Eyes, Allergies | Cetirizine HCl 10mg Caplets, Compare to Leading Brand (300 Count (Pack of 1))

9.9

9.3

9.3

4

Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 30 Count (Packaging may vary)

5

HealthA2Z® Allergy Relief | Cetirizine 10mg | All Day Allergy Relief | Indoor & Outdoor | Relief from Itchy Throat, Sneezing, Runny Noses (300 Count (Pack of 1))

6

Amazon Basic Care Allergy Relief Diphenhydramine HCl 25 mg, Antihistamine Tablets for Symptoms Due to Hay Fever and Upper Respiratory Allergies, 100 Count

9.9

9.7

9.3

7

Xyzal 24 Hour Allergy Relief Medicine, Original Prescription Strength Antihistamine, Levocetirizine Dihydrochloride Tablets, 5 mg, 35 Count

9.7

8.7

8

GoodSense All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 365 Count

9.9

9.9

9

Amazon Basic Care Allergy Relief Loratadine Tablets 10 mg, 90 Count (Packaging may vary)

9.9

9.3

9.1

10

GoodSense Allergy Relief Loratadine Tablets 10 mg, Antihistamine, Allergy Medicine for 24 Hour Allergy Relief, 365 Count

9.9

9.3

9.1

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